Caspase 3 Polyclonal Antibody

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits| large and small| that dimerize to form the active enzyme. This protein cleaves and activates caspases 6| 7 and 9| and the protein itself is processed by caspases 8| 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein| which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

The CASPASE 3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of CASPASE 3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the CASPASE 3 protein. It has been extensively validated for its specificity and affinity towards CASPASE 3, ensuring reliable and accurate results.

The CASPASE 3 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both the proenzyme and the active form of CASPASE 3, enabling the detection of total CASPASE 3 protein levels as well as its activation status. This antibody demonstrates minimal cross-reactivity with other caspases, ensuring specific and precise detection of CASPASE 3.

With its high sensitivity, the CASPASE 3 Polyclonal Antibody allows for the detection of low-abundance CASPASE 3 protein in samples with limited availability. It offers a reliable and reproducible solution for researchers studying apoptosis, as CASPASE 3 plays a crucial role in this process. The antibody's robust performance and consistent results make it an ideal choice for both basic research and clinical applications.

The CASPASE 3 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effective and efficient experiments. The antibody is manufactured under strict quality control standards, guaranteeing batch-to-batch consistency and reliability.

In summary, the CASPASE 3 Polyclonal Antibody is a highly specific and sensitive tool that enables accurate detection and quantification of CASPASE 3 protein. Its exceptional performance, versatility, and reliability make it an invaluable asset for researchers in the field of apoptosis and beyond.