Caspase 3 p17 Polyclonal Antibody

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits| large and small| that dimerize to form the active enzyme. This protein cleaves and activates caspases 6| 7 and 9| and the protein itself is processed by caspases 8| 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein| which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

The Caspase 3 p17 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Caspase 3 p17 protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Caspase 3 p17 Polyclonal Antibody is a valuable tool for researchers studying apoptosis and cell death pathways. Caspase 3 is a key enzyme involved in the execution phase of apoptosis, and the p17 fragment is a well-established marker of Caspase 3 activation. This antibody is capable of detecting the p17 fragment of Caspase 3 with high specificity and sensitivity, making it an ideal choice for researchers looking to study the role of Caspase 3 in apoptosis and other cellular processes.

The Caspase 3 p17 Polyclonal Antibody is manufactured to the highest standards of quality and purity, ensuring consistent and reliable results in every experiment. It is supplied in a convenient format, with a range of sizes available to suit the needs of different research projects. With its high specificity, sensitivity, and versatility, the Caspase 3 p17 Polyclonal Antibody is an essential tool for any researcher studying apoptosis and cell death pathways.