NF-κB p105(Phospho-Ser933) Rabbit Polyclonal Antibody

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines| oxidant-free radicals| ultraviolet irradiation| and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different is of 

Introducing the NF-κB p105(Phospho-Ser933) Rabbit Polyclonal Antibody, a highly specialized and meticulously developed product designed to cater to the needs of researchers and scientists in the field of molecular biology. This antibody, derived from rabbit polyclonal sources, exhibits exceptional specificity and sensitivity, making it an invaluable tool for the detection and analysis of NF-κB p105 protein phosphorylated at Ser933.

With its advanced formulation, this antibody offers unparalleled performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its ability to recognize and bind specifically to the phosphorylated form of NF-κB p105 at Ser933 ensures accurate and reliable results, enabling researchers to delve deeper into the intricate mechanisms of cellular signaling pathways.

The NF-κB p105(Phospho-Ser933) Rabbit Polyclonal Antibody has undergone rigorous quality control measures to ensure its consistency and reliability. Each batch is meticulously tested to guarantee high specificity, minimal cross-reactivity, and low background noise, thereby providing researchers with the utmost confidence in their experimental outcomes.

Furthermore, this antibody has been validated for use in a wide range of species, including human, mouse, and rat, allowing for versatile applications across various model systems. Its compatibility with multiple experimental techniques and its ability to perform consistently across different species make it an indispensable tool for researchers seeking to unravel the complexities of NF-κB p105 signaling.

In summary, the NF-κB p105(Phospho-Ser933) Rabbit Polyclonal Antibody stands as a pinnacle of scientific excellence, offering researchers an exceptional tool to explore the intricate world of molecular biology. Its specificity, sensitivity, and versatility make it an indispensable asset in the pursuit of groundbreaking discoveries and advancements in the field.