AMPK alpha 1/2 Polyclonal Antibody

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

The AMPK alpha 1/2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of AMP-activated protein kinase (AMPK) alpha 1 and alpha 2 subunits. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity in detecting AMPK alpha 1 and alpha 2 subunits in various biological samples.

The AMPK alpha 1/2 Polyclonal Antibody is an essential tool for researchers studying the regulation of energy metabolism and cellular stress responses. It is particularly useful for investigating the role of AMPK in various physiological and pathological conditions, including diabetes, cancer, and cardiovascular diseases.

This antibody is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It is also compatible with a wide range of sample types, including tissue lysates, cell lysates, and purified proteins.

In summary, the AMPK alpha 1/2 Polyclonal Antibody is a reliable and effective tool for the detection of AMPK alpha 1 and alpha 2 subunits in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying the regulation of energy metabolism and cellular stress responses.