1C04 Rabbit Polyclonal Antibody

HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide| exons 2 and 3 encode the alpha1 and alpha2 domain| which both bind the peptide| exon 4 encodes the alpha3 domain| exon 5 encodes the transmembrane region| and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described.

The 1C04 Rabbit Polyclonal Antibody is a highly specific and reliable tool for various research applications. This antibody is produced using high-quality rabbit immunoglobulins, ensuring exceptional sensitivity and specificity in detecting the target protein. With its polyclonal nature, this antibody exhibits a broad range of epitope recognition, making it suitable for a wide array of experimental settings.

The 1C04 Rabbit Polyclonal Antibody has been extensively validated and optimized for use in immunohistochemistry (IHC), immunofluorescence (IF), western blotting (WB), and other related techniques. Its exceptional performance in these applications allows for accurate and reproducible results, enabling researchers to confidently analyze protein expression and localization in various biological samples.

This antibody is supplied as a liquid formulation, conveniently packaged in a vial with an appropriate volume for multiple experiments. It is provided in a ready-to-use format, eliminating the need for time-consuming and error-prone antibody dilutions. The 1C04 Rabbit Polyclonal Antibody is compatible with a wide range of sample types, including tissue sections, cell cultures, and whole-cell lysates.

Furthermore, this antibody exhibits excellent stability, ensuring consistent performance over time. It is recommended to store the antibody at -20°C for long-term storage, allowing for multiple uses without compromising its quality. The 1C04 Rabbit Polyclonal Antibody is also available in different sizes to accommodate various experimental needs.

In summary, the 1C04 Rabbit Polyclonal Antibody is a reliable and versatile tool for protein detection and analysis. Its high specificity, broad epitope recognition, and compatibility with multiple techniques make it an ideal choice for researchers in the field. With its exceptional performance and ease of use, this antibody is an invaluable asset for advancing scientific discoveries in various biological disciplines.