Phospho-Catenin-Beta (S552) Polyclonal Antibody

Catenin beta 1 encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Catenin beta 1 also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, catenin beta 1 binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in CTNNB1 are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for CTNNB1.

Introducing the Phospho-Catenin-Beta (S552) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of molecular biology. This antibody, derived from a polyclonal source, exhibits exceptional specificity and sensitivity, enabling precise detection and analysis of the phosphorylated form of Catenin-Beta at serine 552 residue.

Crafted with utmost precision and utilizing state-of-the-art technology, this antibody guarantees reliable and reproducible results, making it an indispensable asset for scientists and researchers alike. Its high affinity towards the phosphorylated Catenin-Beta (S552) epitope ensures accurate identification and quantification of this critical protein modification, thereby unraveling intricate cellular signaling pathways and shedding light on various physiological and pathological processes.

The Phospho-Catenin-Beta (S552) Polyclonal Antibody boasts an extensive range of applications, including but not limited to immunoblotting, immunoprecipitation, immunofluorescence, and immunohistochemistry. Its versatility allows for comprehensive investigations into diverse biological systems, enabling researchers to delve deeper into the intricate mechanisms underlying cellular functions.

Furthermore, this antibody exhibits exceptional stability and longevity, ensuring consistent performance over extended periods. Its robust formulation guarantees minimal background noise, thereby enhancing signal-to-noise ratios and facilitating accurate interpretation of experimental data.

In summary, the Phospho-Catenin-Beta (S552) Polyclonal Antibody represents a pinnacle of scientific innovation, offering unparalleled specificity, sensitivity, and versatility. With its remarkable performance and reliability, this antibody serves as an invaluable tool for elucidating the complex world of molecular biology, empowering researchers to make groundbreaking discoveries and advance our understanding of cellular processes.