Phospho-Bax (T167) Polyclonal Antibody

The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.

Introducing the Phospho-Bax (T167) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of cellular biology. This antibody, derived from a polyclonal source, exhibits exceptional specificity and sensitivity in detecting the phosphorylated form of Bax at threonine residue 167.

Crafted with utmost precision, this antibody showcases an unparalleled affinity towards the phosphorylated Bax protein, enabling researchers to delve into the intricate mechanisms underlying cellular apoptosis. Its robust performance ensures accurate and reliable results, empowering scientists to unravel the complexities of this crucial biological process.

The Phospho-Bax (T167) Polyclonal Antibody is meticulously validated through rigorous quality control measures, guaranteeing its exceptional performance across a wide range of applications. Its versatility allows for utilization in various experimental techniques, including Western blotting, immunoprecipitation, and immunofluorescence, thereby facilitating comprehensive investigations into the phosphorylation status of Bax.

With its user-friendly nature, this antibody offers seamless integration into existing laboratory protocols, streamlining experimental workflows and enhancing overall efficiency. Its compatibility with diverse sample types, including human, mouse, and rat, further broadens its applicability, catering to a wide array of research needs.

In summary, the Phospho-Bax (T167) Polyclonal Antibody stands as an indispensable asset for researchers seeking to unravel the intricate mechanisms governing cellular apoptosis. Its exceptional specificity, sensitivity, and versatility make it an invaluable tool in advancing scientific understanding in the realm of cellular biology.