Phospho-4E-BP1 (T70) Polyclonal Antibody

EIF4EBP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

The Phospho-4E-BP1 (T70) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated 4E-BP1 at threonine 70 residue. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the target antigen.

The Phospho-4E-BP1 (T70) Polyclonal Antibody is extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and selectivity, enabling accurate and reliable detection of phosphorylated 4E-BP1 in complex biological samples.

This antibody is manufactured under stringent quality control measures to ensure batch-to-batch consistency and reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation steps.

The Phospho-4E-BP1 (T70) Polyclonal Antibody is an indispensable tool for researchers studying the regulation of protein translation and its impact on cellular processes. Its high specificity and sensitivity make it an ideal choice for investigating the phosphorylation status of 4E-BP1 at threonine 70 residue in various experimental settings.

Order the Phospho-4E-BP1 (T70) Polyclonal Antibody today and unlock new insights into the intricate mechanisms governing protein synthesis and its implications in disease development and therapeutic interventions.