Phospho-AIP4 (Y420) Polyclonal Antibody

ITCH (itchy E3 ubiquitin protein ligase) encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in ITCH are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for ITCH.

Introducing the Phospho-AIP4 (Y420) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of molecular biology. This antibody, developed with utmost precision and expertise, is specifically tailored to detect and analyze the phosphorylation of AIP4 at the Y420 residue.

Crafted with the highest quality materials and adhering to rigorous manufacturing standards, this polyclonal antibody guarantees exceptional sensitivity and specificity. Its unique composition enables it to recognize and bind to the phosphorylated form of AIP4 at the Y420 site, ensuring accurate and reliable results.

The Phospho-AIP4 (Y420) Polyclonal Antibody is an indispensable asset for scientists and researchers seeking to unravel the intricate mechanisms underlying cellular signaling pathways. By targeting the phosphorylation of AIP4, this antibody enables the investigation of crucial cellular processes, including protein degradation, endocytosis, and ubiquitination.

With its exceptional performance, this antibody empowers researchers to delve deeper into the complexities of molecular interactions and signaling cascades. Its versatility extends to various applications, including Western blotting, immunoprecipitation, and immunofluorescence, allowing for comprehensive analysis across diverse experimental setups.

Furthermore, this polyclonal antibody exhibits remarkable stability and longevity, ensuring consistent and reproducible results over extended periods. Its robust design and compatibility with multiple species, including human, mouse, and rat, make it an invaluable tool for a wide range of scientific investigations.

In summary, the Phospho-AIP4 (Y420) Polyclonal Antibody represents a breakthrough in molecular biology research, offering unparalleled sensitivity, specificity, and versatility. With its ability to detect and analyze the phosphorylation of AIP4 at the Y420 residue, this antibody empowers scientists to unravel the intricate mechanisms governing cellular signaling pathways. Invest in this exceptional scientific tool and unlock new frontiers in molecular biology research.