Phospho-Adducin  Alpha (T445) Polyclonal Antibody

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

The Phospho-Adducin Alpha (T445) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated Adducin Alpha at threonine 445 residue. This antibody is produced using advanced techniques to ensure high affinity and specificity, making it an ideal choice for various applications in research and diagnostics.

The Phospho-Adducin Alpha (T445) Polyclonal Antibody exhibits exceptional performance in immunoblotting, immunohistochemistry, and immunofluorescence assays. It recognizes the phosphorylated form of Adducin Alpha with remarkable sensitivity, enabling accurate and reliable detection even at low expression levels. This antibody demonstrates minimal cross-reactivity with non-phosphorylated Adducin Alpha and other related proteins, ensuring precise and specific results.

With its superior quality and performance, the Phospho-Adducin Alpha (T445) Polyclonal Antibody is an invaluable tool for investigating the role of phosphorylated Adducin Alpha in various cellular processes and signaling pathways. It enables researchers to gain insights into the regulation and function of Adducin Alpha in normal and pathological conditions.

The Phospho-Adducin Alpha (T445) Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and consistent results. It is available in various sizes to accommodate different experimental needs. Each batch of antibody undergoes rigorous quality control tests to ensure batch-to-batch consistency and reproducibility.

In summary, the Phospho-Adducin Alpha (T445) Polyclonal Antibody is a reliable and specific tool for the detection and quantification of phosphorylated Adducin Alpha. Its exceptional performance and versatility make it an essential component in various research and diagnostic applications.