Phospho-14-3-3 Zeta (S58) Polyclonal Antibody

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for YWHAZ.

The Phospho-14-3-3 Zeta (S58) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated 14-3-3 Zeta protein at serine 58 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

The 14-3-3 Zeta protein plays a crucial role in various cellular processes, including signal transduction, cell cycle regulation, and apoptosis. Phosphorylation of the serine 58 residue has been implicated in the modulation of 14-3-3 Zeta protein function and its interaction with other proteins. Therefore, the Phospho-14-3-3 Zeta (S58) Polyclonal Antibody serves as an invaluable tool for researchers studying the regulatory mechanisms and functional implications of 14-3-3 Zeta phosphorylation.

This antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated 14-3-3 Zeta protein and other related proteins, ensuring accurate and reliable results.

The Phospho-14-3-3 Zeta (S58) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy integration into various experimental protocols. The antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional specificity, sensitivity, and versatility, the Phospho-14-3-3 Zeta (S58) Polyclonal Antibody is an indispensable tool for researchers investigating the role of 14-3-3 Zeta phosphorylation in cellular processes. Its reliable performance and ease of use make it an ideal choice for both basic research and drug development studies.