Phospho-ATP-citrate synthase (S455) Polyclonal Antibody

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Introducing the Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of molecular biology. This antibody, derived from a polyclonal source, exhibits exceptional specificity and sensitivity, enabling accurate detection and analysis of the phosphorylated ATP-citrate synthase at serine 455 residue.

Crafted with utmost precision, this antibody showcases unparalleled affinity towards the target protein, ensuring reliable and reproducible results. Its robust performance is further enhanced by its ability to recognize the phosphorylated form of ATP-citrate synthase, specifically at the serine 455 site, enabling researchers to delve deeper into the intricate mechanisms underlying cellular processes.

The Phospho-ATP-citrate synthase (S455) Polyclonal Antibody is meticulously validated through rigorous quality control measures, guaranteeing its reliability and consistency. Its exceptional specificity is confirmed through various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence, ensuring its versatility across diverse applications.

This antibody is supplied in a convenient and user-friendly format, facilitating seamless integration into existing laboratory protocols. Its optimized formulation ensures stability and longevity, allowing for prolonged usage without compromising performance. Additionally, it exhibits minimal cross-reactivity, minimizing the risk of false-positive results and ensuring accurate interpretation of experimental data.

In summary, the Phospho-ATP-citrate synthase (S455) Polyclonal Antibody represents a breakthrough in molecular biology research, offering researchers an invaluable tool to unravel the complexities of cellular processes. With its exceptional specificity, sensitivity, and reliability, this antibody is poised to revolutionize the field, empowering scientists to make significant strides in understanding the intricate mechanisms governing cellular function.