Phospho-Artemis (S516) Polyclonal Antibody

DCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.

Introducing the Phospho-Artemis (S516) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of molecular biology. This antibody, derived from a polyclonal source, exhibits exceptional specificity and sensitivity, enabling precise detection and analysis of phosphorylated Artemis at the serine 516 residue.

Crafted with utmost precision and utilizing state-of-the-art technology, this antibody offers researchers an invaluable resource to unravel the intricate mechanisms underlying DNA repair and recombination processes. By targeting the phosphorylated form of Artemis, this antibody enables the investigation of critical signaling pathways involved in cellular responses to DNA damage, thereby shedding light on the fundamental principles governing genome stability.

The Phospho-Artemis (S516) Polyclonal Antibody boasts an exceptional affinity for its target, ensuring reliable and reproducible results across a wide range of experimental applications. Its versatility extends to various techniques, including Western blotting, immunoprecipitation, and immunofluorescence, empowering researchers to explore diverse aspects of Artemis phosphorylation with utmost confidence.

Furthermore, this antibody has been rigorously validated through meticulous quality control measures, guaranteeing its exceptional performance and reliability. Its robustness is further enhanced by its compatibility with multiple species, including human, mouse, and rat, facilitating cross-species research and enabling comprehensive investigations across various model systems.

In summary, the Phospho-Artemis (S516) Polyclonal Antibody represents a breakthrough tool for researchers seeking to unravel the intricate molecular mechanisms governing DNA repair and recombination. With its exceptional specificity, sensitivity, and versatility, this antibody empowers scientists to delve deeper into the fascinating world of Artemis phosphorylation, ultimately advancing our understanding of genome stability and contributing to the advancement of scientific knowledge.