Phospho-BRCA2 (S3291) Polyclonal Antibody

Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.

Introducing the Phospho-BRCA2 (S3291) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of molecular biology. This antibody, derived from a polyclonal source, exhibits exceptional specificity and sensitivity, enabling precise detection and analysis of the phosphorylated BRCA2 protein at serine 3291 residue.

Crafted with utmost precision and utilizing state-of-the-art technology, this antibody offers researchers an invaluable resource to unravel the intricate mechanisms underlying BRCA2 phosphorylation. Its polyclonal nature ensures a diverse range of epitope recognition, enhancing the versatility and reliability of experimental outcomes.

The Phospho-BRCA2 (S3291) Polyclonal Antibody boasts an exceptional affinity for the phosphorylated BRCA2 protein, enabling accurate identification and quantification of this critical molecular marker. Its high specificity ensures minimal cross-reactivity, thereby minimizing the risk of false-positive results and ensuring the utmost reliability in experimental analyses.

This antibody's exceptional sensitivity empowers researchers to detect even the most minute quantities of phosphorylated BRCA2, facilitating the exploration of subtle molecular events and enabling comprehensive investigations into the functional implications of BRCA2 phosphorylation. Its robust performance guarantees consistent and reproducible results, enabling researchers to confidently delve into the complexities of BRCA2 biology.

Furthermore, the Phospho-BRCA2 (S3291) Polyclonal Antibody is meticulously validated through rigorous quality control measures, ensuring its reliability and reproducibility across various experimental conditions. Its compatibility with a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence, further enhances its versatility and utility in diverse research settings.

In summary, the Phospho-BRCA2 (S3291) Polyclonal Antibody represents a breakthrough in molecular biology research, offering scientists an indispensable tool to unravel the intricacies of BRCA2 phosphorylation. With its exceptional specificity, sensitivity, and reliability, this antibody empowers researchers to advance their understanding of BRCA2 biology, paving the way for groundbreaking discoveries in the field.