Phospho-Casein Kinase I Alpha (Y321) Polyclonal Antibody

CSNK1A1 (Casein Kinase 1 Alpha 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Infectious disease. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CSNK1G2. asein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at Ser-45. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed: 11955436, PubMed: 1409656, PubMed: 18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed: 23902688). asein kinase I (CK1) is a monomeric serine-threonine protein kinase with 7 isoforms: alpha, beta, gamma1, gamma2, gamma3, delta and epsilon. CK1 is involved in many cellular processes including DNA repair, cell division, nuclear localization and membrane transport. Isoforms are also integral to development.

Introducing the Phospho-Casein Kinase I Alpha (Y321) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of protein phosphorylation. This high-quality antibody is specifically tailored to target the phosphorylated form of Casein Kinase I Alpha at the tyrosine 321 residue, enabling precise detection and analysis of this critical post-translational modification.

Crafted with utmost precision and utilizing state-of-the-art technology, this polyclonal antibody exhibits exceptional specificity and sensitivity, ensuring accurate and reliable results. Its affinity for the phosphorylated Casein Kinase I Alpha at Y321 guarantees minimal cross-reactivity, thereby minimizing any potential interference from non-specific binding events.

The Phospho-Casein Kinase I Alpha (Y321) Polyclonal Antibody is meticulously validated through rigorous quality control measures, ensuring consistent performance across various experimental conditions. Its robustness and reproducibility make it an indispensable tool for researchers seeking to unravel the intricate mechanisms underlying protein phosphorylation and its impact on cellular processes.

This antibody is supplied in a convenient and user-friendly format, allowing for easy integration into existing laboratory protocols. Its versatility enables a wide range of applications, including Western blotting, immunoprecipitation, immunofluorescence, and immunohistochemistry, empowering researchers to explore diverse avenues of investigation.

In summary, the Phospho-Casein Kinase I Alpha (Y321) Polyclonal Antibody represents a breakthrough in the field of protein phosphorylation research. With its exceptional specificity, sensitivity, and reliability, this antibody is poised to revolutionize the understanding of Casein Kinase I Alpha phosphorylation and its implications in cellular signaling pathways. Embrace this cutting-edge tool and unlock new frontiers in your scientific endeavors.