Phospho-C/EBP  Alpha (T226) Polyclonal Antibody

CEBPA encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The CCAAT/enhancer binding protein alpha functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.

The Phospho-C/EBP Alpha (T226) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of phosphorylated C/EBP Alpha protein. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The Phospho-C/EBP Alpha (T226) Polyclonal Antibody exhibits a high affinity towards the phosphorylated threonine 226 residue of the C/EBP Alpha protein. This phosphorylation event plays a crucial role in the regulation of C/EBP Alpha's transcriptional activity, making it an essential target for studying cellular processes such as cell differentiation, proliferation, and metabolism.

With its superior performance, this antibody enables researchers to investigate the phosphorylation status of C/EBP Alpha in various biological samples, including cell lysates and tissue extracts. Its exceptional specificity ensures minimal cross-reactivity with non-phosphorylated C/EBP Alpha or other related proteins, guaranteeing accurate and reliable results.

The Phospho-C/EBP Alpha (T226) Polyclonal Antibody is supplied as a liquid formulation, allowing for easy handling and convenient storage. It is provided in a ready-to-use format, eliminating the need for time-consuming antibody preparation. This antibody is compatible with a wide range of experimental techniques, facilitating its integration into diverse research workflows.

In summary, the Phospho-C/EBP Alpha (T226) Polyclonal Antibody is a highly specific and sensitive tool that enables researchers to investigate the phosphorylation status of C/EBP Alpha protein. Its exceptional performance and compatibility with various applications make it an invaluable asset for studying cellular processes and unraveling the intricate mechanisms underlying C/EBP Alpha-mediated regulation.