Phospho-Btk (Y223) Polyclonal Antibody

Bruton tyrosine kinase encoded by BTK plays a crucial role in B-cell development. Mutations in BTK cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

The Phospho-Btk (Y223) Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of phosphorylated Bruton's tyrosine kinase (Btk) at tyrosine 223 residue. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated for use in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The Phospho-Btk (Y223) Polyclonal Antibody is an essential tool for researchers studying the role of Btk in various cellular processes, including B-cell development, differentiation, and activation. This antibody is highly specific to the phosphorylated form of Btk at tyrosine 223 residue, making it an ideal tool for studying the activation of Btk in response to various stimuli.

The Phospho-Btk (Y223) Polyclonal Antibody is manufactured using state-of-the-art techniques and is rigorously tested to ensure high specificity and sensitivity. This antibody is supplied in a convenient format, making it easy to use in a variety of applications.

Overall, the Phospho-Btk (Y223) Polyclonal Antibody is a reliable and effective tool for researchers studying the role of Btk in various cellular processes. Its high specificity and sensitivity make it an ideal choice for detecting phosphorylated Btk at tyrosine 223 residue in a variety of applications.