Phospho-CaMKII Alpha/Beta/Delta (T305) Polyclonal Antibody

Calcium/calmodulin dependent protein kinase II beta belongs to the serine/threonine protein kinase family and to the Ca (2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of CAMK2B is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants.

The Phospho-CaMKII Alpha/Beta/Delta (T305) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of phosphorylated Calcium/Calmodulin-dependent protein kinase II (CaMKII) isoforms, including Alpha, Beta, and Delta, at the T305 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity.

CaMKII is a crucial regulator of various cellular processes, including synaptic plasticity, learning, and memory. Phosphorylation of CaMKII at the T305 residue has been implicated in the modulation of its activity and function. Therefore, the Phospho-CaMKII Alpha/Beta/Delta (T305) Polyclonal Antibody serves as an invaluable tool for researchers interested in investigating the role of CaMKII phosphorylation in cellular signaling pathways and disease mechanisms.

This antibody exhibits outstanding performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It has been extensively validated for its specificity and sensitivity, ensuring accurate and reproducible results. The Phospho-CaMKII Alpha/Beta/Delta (T305) Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional quality and reliability, the Phospho-CaMKII Alpha/Beta/Delta (T305) Polyclonal Antibody is an indispensable tool for researchers in the fields of neuroscience, cell biology, and molecular biology. It enables precise and detailed investigations into the phosphorylation status and functional implications of CaMKII isoforms, contributing to a deeper understanding of cellular processes and disease mechanisms.