Phospho-Catenin-Beta (S33) Polyclonal Antibody

Catenin beta-1 encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.

Introducing the Phospho-Catenin-Beta (S33) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of molecular biology. This antibody, derived from a polyclonal source, exhibits exceptional specificity and sensitivity, enabling precise detection and analysis of the phosphorylated form of Catenin-Beta at serine residue 33.

Crafted with utmost precision and utilizing state-of-the-art technology, this antibody offers researchers an invaluable resource for investigating the intricate signaling pathways involving Catenin-Beta phosphorylation. Its high affinity for the phosphorylated epitope ensures accurate identification and quantification of this critical post-translational modification, thereby unraveling the underlying mechanisms governing cellular processes.

The Phospho-Catenin-Beta (S33) Polyclonal Antibody boasts an exceptional performance profile, characterized by its remarkable selectivity and minimal cross-reactivity. This attribute guarantees reliable and reproducible results, empowering researchers to confidently explore the dynamic interplay between Catenin-Beta phosphorylation and various cellular events, including cell adhesion, proliferation, and differentiation.

Furthermore, this antibody's versatility extends to a wide range of applications, encompassing Western blotting, immunoprecipitation, immunofluorescence, and immunohistochemistry. Its compatibility with diverse experimental techniques ensures seamless integration into various research workflows, facilitating comprehensive investigations into the functional implications of Catenin-Beta phosphorylation.

In summary, the Phospho-Catenin-Beta (S33) Polyclonal Antibody represents a breakthrough in molecular biology research, offering scientists an indispensable tool to unravel the complexities of Catenin-Beta phosphorylation. With its exceptional specificity, sensitivity, and versatility, this antibody empowers researchers to delve deeper into the intricate molecular mechanisms governing cellular processes, ultimately advancing our understanding of fundamental biological phenomena.