Phospho-Bad (S136) Polyclonal Antibody

BCL2 associated agonist of cell death encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. BCL2 associated agonist of cell death positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of BCL2 associated agonist of cell death is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of BCL2 associated agonist of cell death. Alternative splicing of BAD results in two transcript variants which encode the same isoform.

Introducing the Phospho-Bad (S136) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of molecular biology. This antibody, derived from a polyclonal source, exhibits exceptional specificity and sensitivity, enabling accurate detection and analysis of phosphorylated Bad at serine 136 residue.

Crafted with utmost precision, this antibody showcases an unparalleled affinity towards the phosphorylated form of Bad, making it an indispensable asset for investigating the intricate signaling pathways associated with cellular apoptosis. Its polyclonal nature ensures a broad recognition spectrum, allowing for comprehensive exploration of diverse experimental models and species.

The Phospho-Bad (S136) Polyclonal Antibody is meticulously validated through rigorous quality control measures, ensuring optimal performance and reproducibility. Its exceptional specificity guarantees minimal cross-reactivity, thereby minimizing the risk of false-positive results and enhancing the reliability of experimental outcomes.

This antibody's versatility extends to various applications, including Western blotting, immunohistochemistry, and immunofluorescence, empowering researchers to delve into the intricate mechanisms underlying cellular processes. Its compatibility with multiple experimental techniques further amplifies its utility, facilitating seamless integration into diverse research workflows.

Furthermore, the Phospho-Bad (S136) Polyclonal Antibody is engineered to exhibit exceptional stability, ensuring prolonged shelf life and consistent performance over time. This attribute, coupled with its cost-effectiveness, renders it an ideal choice for both academic and industrial laboratories seeking to optimize their research endeavors.

In summary, the Phospho-Bad (S136) Polyclonal Antibody stands as an indispensable tool for discerning scientists, offering unparalleled specificity, sensitivity, and versatility. With its exceptional performance, this antibody paves the way for groundbreaking discoveries in the realm of molecular biology, propelling scientific advancements to new heights.