Phospho-Bad (S112) Polyclonal Antibody

BCL2 associated agonist of cell death encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. BCL2 associated agonist of cell death positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of BCL2 associated agonist of cell death is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of BCL2 associated agonist of cell death. Alternative splicing of BAD results in two transcript variants which encode the same isoform.

Introducing the Phospho-Bad (S112) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of cellular signaling pathways. This antibody, developed with utmost precision and expertise, specifically targets the phosphorylated form of Bad at serine 112 residue, enabling researchers to delve into the intricate mechanisms underlying cellular processes.

Crafted with the highest quality materials and adhering to stringent manufacturing standards, this polyclonal antibody exhibits exceptional specificity and sensitivity, ensuring accurate and reliable results. Its unique formulation allows for optimal recognition and binding to the phosphorylated Bad (S112) epitope, thereby facilitating precise detection and quantification of this critical protein modification.

The Phospho-Bad (S112) Polyclonal Antibody is an indispensable tool for elucidating the role of Bad phosphorylation in diverse cellular processes, including apoptosis, cell survival, and metabolism. By enabling researchers to investigate the intricate interplay between phosphorylation events and downstream signaling cascades, this antibody empowers the scientific community to unravel novel insights into the complex regulatory networks governing cellular homeostasis.

With its versatility, this antibody is compatible with various experimental techniques, including Western blotting, immunoprecipitation, and immunofluorescence. Its robust performance across multiple applications ensures seamless integration into diverse research workflows, facilitating comprehensive investigations into the functional implications of Bad phosphorylation.

Furthermore, this polyclonal antibody is accompanied by comprehensive technical support, including detailed protocols and expert guidance, to ensure optimal experimental outcomes. Our dedicated team of scientists is readily available to address any queries or concerns, providing a seamless research experience.

In summary, the Phospho-Bad (S112) Polyclonal Antibody represents a breakthrough tool for researchers seeking to unravel the intricate regulatory mechanisms governing cellular signaling pathways. With its exceptional specificity, sensitivity, and compatibility with various experimental techniques, this antibody empowers scientists to unlock novel insights into the role of Bad phosphorylation in cellular processes. Trust in this meticulously crafted antibody to elevate your research endeavors to unprecedented heights.