Phospho-ATF-2 (T71) Polyclonal Antibody

ATF2 encodes a transcription factor (activating transcription factor 2) that is a member of the leucine zipper family of DNA binding proteins. Activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Activating transcription factor 2 binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Activating transcription factor 2 may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this ATF2.

The Phospho-ATF-2 (T71) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated ATF-2 at threonine 71 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional quality and performance.

ATF-2, also known as activating transcription factor 2, is a key transcription factor involved in various cellular processes, including stress response, cell proliferation, and differentiation. Phosphorylation of ATF-2 at threonine 71 plays a crucial role in its activation and subsequent regulation of target gene expression.

The Phospho-ATF-2 (T71) Polyclonal Antibody exhibits excellent specificity towards phosphorylated ATF-2 at threonine 71, enabling precise and reliable detection in various experimental applications, such as Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its specificity and sensitivity, ensuring accurate and reproducible results.

This antibody is produced using high-quality materials and rigorous manufacturing processes, guaranteeing batch-to-batch consistency and reliability. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation.

With its exceptional performance and reliability, the Phospho-ATF-2 (T71) Polyclonal Antibody is an indispensable tool for researchers studying ATF-2 signaling pathways and its involvement in various cellular processes. Its high specificity and sensitivity make it an ideal choice for both basic research and clinical applications.

Order the Phospho-ATF-2 (T71) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of ATF-2 phosphorylation and its impact on cellular function.