Phospho-AMPK Alpha1 (S496) Polyclonal Antibody

The protein encoded by PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1) belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Introducing the Phospho-AMPK Alpha1 (S496) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of cellular signaling pathways. This highly specific antibody is engineered to target and detect the phosphorylated form of AMPK Alpha1 at serine residue 496, enabling precise investigation of this critical post-translational modification.

Crafted with utmost precision and utilizing state-of-the-art technology, this polyclonal antibody exhibits exceptional sensitivity and specificity, ensuring accurate and reliable results. Its robust performance is attributed to the rigorous validation process it undergoes, guaranteeing optimal performance across a wide range of applications, including immunoblotting, immunoprecipitation, and immunofluorescence.

The Phospho-AMPK Alpha1 (S496) Polyclonal Antibody boasts an impressive affinity for its target, enabling researchers to explore the intricate mechanisms underlying AMPK signaling with unparalleled precision. Its exceptional selectivity ensures minimal cross-reactivity, thereby minimizing the risk of false-positive results and enhancing experimental accuracy.

This antibody is meticulously manufactured using high-quality materials and adheres to stringent quality control measures, ensuring batch-to-batch consistency and reproducibility. Its long shelf life and stability make it an ideal choice for long-term experiments and extended storage.

In summary, the Phospho-AMPK Alpha1 (S496) Polyclonal Antibody represents a breakthrough in scientific research, empowering investigators to delve deeper into the complexities of cellular signaling pathways. With its exceptional sensitivity, specificity, and reliability, this antibody is an indispensable tool for elucidating the role of AMPK Alpha1 phosphorylation in various physiological and pathological processes.