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SKU:BT-AP09785

Beta-1,4-Gal-T2 Polyclonal Antibody

Beta-1,4-Gal-T2 Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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B4GALT2 (beta-1,4-galactosyltransferase 2) is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: glcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by B4GALT2 synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding two different isoforms have been found for B4GALT2.

Introducing the Beta-1,4-Gal-T2 Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of glycobiology. This high-quality antibody is specifically developed to target and detect the Beta-1,4-Gal-T2 protein, enabling precise analysis and characterization of its expression and function.

Crafted with utmost precision and utilizing state-of-the-art techniques, this polyclonal antibody exhibits exceptional specificity and sensitivity, ensuring accurate and reliable results. Its robust binding affinity towards the Beta-1,4-Gal-T2 protein guarantees optimal detection, even in low abundance or challenging experimental conditions.

The Beta-1,4-Gal-T2 Polyclonal Antibody boasts an extensive range of applications, making it an invaluable asset for researchers across various disciplines. From fundamental investigations into glycosylation processes to elucidating the role of Beta-1,4-Gal-T2 in disease pathogenesis, this antibody empowers scientists to delve deeper into the intricate world of glycobiology.

With its user-friendly format, this antibody offers unparalleled ease of use, streamlining experimental workflows and saving valuable time. Its compatibility with a diverse array of techniques, including Western blotting, immunohistochemistry, and immunofluorescence, ensures versatility and flexibility in experimental design.

Furthermore, this Beta-1,4-Gal-T2 Polyclonal Antibody is meticulously validated through rigorous quality control measures, guaranteeing exceptional performance and reproducibility. Each batch is subjected to stringent testing to ensure batch-to-batch consistency, providing researchers with the utmost confidence in their experimental outcomes.

In summary, the Beta-1,4-Gal-T2 Polyclonal Antibody represents a pinnacle of scientific innovation, offering researchers an indispensable tool to unravel the complexities of glycobiology. With its exceptional specificity, sensitivity, and versatility, this antibody is poised to revolutionize research in the field, enabling groundbreaking discoveries and advancing our understanding of biological processes.

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