ZC3H13 Polyclonal Antibody

The zinc finger CCCH domain-containing protein 13 (ZC3H13) is a 1668 amino acid protein that contains one C3H1-type zinc finger. ZC3H13 is phosphorylated upon DNA damage, most likely by ATM or ATR. Two isoforms of ZC3H13 exists as a result of alternative splicing events. The gene encoding ZC3H13 maps to chromosome 13, which contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

The ZC3H13 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of ZC3H13 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, ensuring its exceptional sensitivity and specificity.

The ZC3H13 Polyclonal Antibody exhibits a broad range of applications, making it an invaluable asset for researchers in diverse fields such as molecular biology, biochemistry, and cell biology. It is particularly useful for investigating the role of ZC3H13 in cellular processes, including RNA metabolism, transcriptional regulation, and post-transcriptional modifications.

This antibody has been rigorously validated through multiple experimental approaches, guaranteeing its superior performance and reliability. It demonstrates minimal cross-reactivity with other proteins, ensuring accurate and precise results. Furthermore, it exhibits excellent stability and reproducibility, making it an ideal choice for long-term studies and large-scale experiments.

The ZC3H13 Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided as a liquid formulation, eliminating the need for time-consuming reconstitution. Additionally, it is compatible with various detection methods, including Western blotting, immunofluorescence, and immunohistochemistry, enabling versatile applications and facilitating comprehensive protein analysis.

In summary, the ZC3H13 Polyclonal Antibody is a superior research tool that offers exceptional sensitivity, specificity, and versatility. Its reliable performance and broad range of applications make it an indispensable asset for scientists aiming to unravel the intricate mechanisms underlying ZC3H13 protein function.