V-ATPase H Polyclonal Antibody

ATP6V1H encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The V-type proton ATPase subunit H is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

The V-ATPase H Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of V-ATPase H subunit in various biological samples. This antibody is produced through a rigorous process of immunization using a purified recombinant V-ATPase H protein, ensuring high affinity and specificity towards the target antigen.

The V-ATPase H Polyclonal Antibody exhibits exceptional sensitivity and selectivity, making it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to investigate the expression and localization of V-ATPase H subunit in different tissues and cell types, facilitating the understanding of its role in various physiological and pathological processes.

With its superior performance and consistent results, the V-ATPase H Polyclonal Antibody offers a valuable tool for both basic research and clinical studies. Its high-quality formulation ensures minimal background noise and maximum signal intensity, allowing for accurate and reliable data interpretation. Furthermore, this antibody is validated for use in multiple species, including human, mouse, and rat, providing versatility and flexibility in experimental design.

In summary, the V-ATPase H Polyclonal Antibody is a top-tier research reagent that guarantees exceptional performance and reliability. Its specificity, sensitivity, and versatility make it an indispensable tool for scientists and researchers studying V-ATPase H subunit and its involvement in various biological processes.