UBE2D2 Polyclonal Antibody

Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. UBE2D2 encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene.

The UBE2D2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of UBE2D2 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity towards UBE2D2.

UBE2D2, also known as Ubiquitin-conjugating enzyme E2 D2, plays a crucial role in the ubiquitin-proteasome system, which is responsible for the targeted degradation of proteins. It functions by conjugating ubiquitin molecules to target proteins, marking them for degradation. UBE2D2 has been implicated in various cellular processes, including cell cycle regulation, DNA repair, and protein quality control.

The UBE2D2 Polyclonal Antibody has been extensively validated for its specificity and performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without compromising its quality. The UBE2D2 Polyclonal Antibody is suitable for use in both research and diagnostic settings, enabling the investigation of UBE2D2 protein expression in various biological contexts.

In summary, the UBE2D2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of UBE2D2 protein expression. Its advanced immunization techniques, high affinity, and sensitivity make it an ideal choice for researchers and clinicians studying the role of UBE2D2 in cellular processes and disease mechanisms.