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SKU:BT-AP09282

TTK Polyclonal Antibody

TTK Polyclonal Antibody

Regular price $275.00 USD
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TTK (TTK protein kinase) encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

The TTK Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect the TTK protein in various biological samples. This antibody has been extensively validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The TTK protein, also known as the dual specificity protein kinase TTK, is a key regulator of cell division and is essential for proper chromosome segregation during mitosis. Dysregulation of TTK expression has been implicated in various diseases, including cancer, making it an important target for research and therapeutic development.

The TTK Polyclonal Antibody has been produced using high-quality materials and rigorous quality control measures to ensure optimal performance and reproducibility. It is available in various sizes and formats to suit different experimental needs.

Overall, the TTK Polyclonal Antibody is a reliable and effective tool for researchers studying the role of TTK in various biological processes and diseases. Its high specificity and sensitivity make it a valuable addition to any laboratory's toolkit.

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