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SKU:BT-AP09153

TPO Polyclonal Antibody

TPO Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.

The TPO Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of thyroid peroxidase (TPO) protein. This antibody is produced by immunizing animals with a purified recombinant TPO protein, ensuring its high affinity and specificity towards TPO.

The TPO Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Its superior sensitivity allows for the accurate detection of TPO protein even at low concentrations, making it an invaluable tool for researchers and clinicians studying thyroid-related disorders.

This antibody is manufactured under stringent quality control measures to ensure batch-to-batch consistency and reliability. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. The TPO Polyclonal Antibody is compatible with a wide range of sample types, including tissue lysates, cell lysates, and serum, facilitating its versatile application in various research settings.

With its exceptional specificity, sensitivity, and ease of use, the TPO Polyclonal Antibody is an indispensable tool for researchers and clinicians seeking to unravel the complexities of thyroid-related diseases. Its reliable performance and consistent results make it an ideal choice for accurate and reproducible experiments, ultimately contributing to advancements in the field of thyroid research and clinical diagnostics.

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