TNF-R2 Polyclonal Antibody

Tumor necrosis factor receptor superfamily member 1B encoded by TNFRSF1B is a member of the TNF-receptor superfamily. Tumor necrosis factor receptor superfamily member 1B and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

The TNF-R2 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of TNF-R2 protein expression. This antibody is produced using advanced techniques, ensuring high affinity and specificity towards TNF-R2.

TNF-R2, also known as tumor necrosis factor receptor superfamily member 1B (TNFRSF1B), is a cell surface receptor that plays a crucial role in the regulation of immune responses and inflammation. It is involved in various physiological and pathological processes, including cell survival, proliferation, and apoptosis.

The TNF-R2 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and flow cytometry. It enables researchers to accurately analyze TNF-R2 expression levels in various tissues and cell types.

This antibody is manufactured under strict quality control standards, ensuring reproducibility and reliability in experimental results. It has been extensively validated in multiple research studies, demonstrating its superior performance and consistency.

With its exceptional sensitivity and specificity, the TNF-R2 Polyclonal Antibody is an indispensable tool for researchers studying the role of TNF-R2 in various biological processes and diseases. Its high-quality formulation and reliable performance make it an ideal choice for both basic research and clinical applications.