TNF-IP 8 Polyclonal Antibody

TNFAIP8 (TNF Alpha Induced Protein 8) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include cysteine-type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of this gene is TNFAIP8L2. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

The TNF-IP 8 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of TNF-IP 8 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human TNF-IP 8 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards TNF-IP 8 protein, making it an ideal tool for various research applications.

The TNF-IP 8 Polyclonal Antibody has been extensively validated for its performance in various immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been shown to detect TNF-IP 8 protein in a wide range of species, including human, mouse, and rat. The antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using protein A chromatography.

This antibody is an essential tool for researchers studying the role of TNF-IP 8 protein in various biological processes, including inflammation, immune response, and cancer. Its high specificity and sensitivity make it an ideal reagent for the detection and quantification of TNF-IP 8 protein in complex biological samples, such as serum, plasma, and tissue lysates.

In summary, the TNF-IP 8 Polyclonal Antibody is a highly specific and sensitive immunological reagent that is essential for researchers studying the role of TNF-IP 8 protein in various biological processes. Its high affinity and specificity make it an ideal tool for various research applications, including Western blotting, immunohistochemistry, and ELISA.