TMEM173 Polyclonal Antibody

TMEM173 encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The transmembrane protein 173 is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

The TMEM173 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of TMEM173 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human TMEM173 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity through various assays, including Western blotting, immunohistochemistry, and immunofluorescence.

The TMEM173 Polyclonal Antibody is suitable for use in a wide range of applications, including research studies on innate immune responses, viral infections, and cancer. It has been shown to recognize TMEM173 protein from various species, including human, mouse, and rat. This antibody is provided in a liquid format and can be used for both qualitative and quantitative analysis of TMEM173 protein expression.

In summary, the TMEM173 Polyclonal Antibody is a reliable and high-quality tool for the detection of TMEM173 protein in various biological samples. Its specificity and sensitivity make it an ideal choice for researchers studying innate immune responses, viral infections, and cancer.