TFE3 Polyclonal Antibody

TFE3 (transcription factor binding to IGHM enhancer 3) encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. TFE3 may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.

The TFE3 Polyclonal Antibody is a highly reliable and efficient tool designed for the detection and analysis of TFE3 protein expression in various biological samples. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional specificity and sensitivity.

The TFE3 Polyclonal Antibody exhibits outstanding performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated and proven to deliver consistent and reproducible results, making it an ideal choice for researchers and scientists in the field.

With its superior affinity and selectivity, this antibody enables accurate and precise identification of TFE3 protein in complex biological systems. It recognizes both endogenous and recombinant TFE3 protein, facilitating comprehensive investigations into its expression patterns and cellular localization.

The TFE3 Polyclonal Antibody is manufactured under stringent quality control measures, ensuring batch-to-batch consistency and reliability. It is supplied in a convenient and ready-to-use format, allowing for immediate application in various experimental settings.

In summary, the TFE3 Polyclonal Antibody is a cutting-edge research tool that offers exceptional performance and versatility. Its high specificity, sensitivity, and reliability make it an indispensable asset for scientists and researchers aiming to unravel the intricate mechanisms involving TFE3 protein expression.