TCF-3 Polyclonal Antibody

TCF3 encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

The TCF-3 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of TCF-3 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity towards TCF-3.

The TCF-3 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to investigate the role of TCF-3 in cellular processes, such as gene regulation, development, and differentiation.

With its superior specificity, this antibody allows for accurate and precise identification of TCF-3 protein in complex biological systems. Its robust performance ensures reliable and reproducible results, making it an indispensable tool for both basic research and clinical studies.

The TCF-3 Polyclonal Antibody is manufactured under stringent quality control measures, guaranteeing batch-to-batch consistency and optimal performance. It is supplied in a convenient format, ready-to-use for immediate application.

Choose the TCF-3 Polyclonal Antibody for its exceptional specificity, reliability, and versatility, and unlock new insights into the intricate mechanisms governed by TCF-3 protein.