TBX22 Polyclonal Antibody

TBX22 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for TBX22.

The TBX22 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of TBX22 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the TBX22 protein sequence.

TBX22 is a transcription factor that plays a crucial role in the development and differentiation of various tissues, including the palate, teeth, and craniofacial structures. Mutations in the TBX22 gene have been associated with X-linked cleft palate and ankyloglossia syndrome, highlighting the importance of studying its expression and function.

The TBX22 Polyclonal Antibody exhibits excellent specificity, as demonstrated by Western blot analysis, immunohistochemistry, and immunofluorescence assays. It recognizes endogenous levels of TBX22 protein in a variety of species, including human, mouse, and rat. This antibody has been extensively validated and characterized to ensure reliable and reproducible results.

With its high sensitivity and specificity, the TBX22 Polyclonal Antibody is an invaluable tool for researchers studying the molecular mechanisms underlying craniofacial development and related disorders. Its application extends to a wide range of research areas, including developmental biology, genetics, and regenerative medicine.

For optimal performance, the TBX22 Polyclonal Antibody should be stored at -20°C upon arrival and diluted according to the recommended protocol. It is supplied in a liquid format, allowing for easy handling and convenient use in various experimental techniques.

In summary, the TBX22 Polyclonal Antibody offers researchers a reliable and efficient means to investigate the expression and function of TBX22 protein in diverse biological contexts. Its exceptional specificity and sensitivity make it an indispensable tool for advancing our understanding of craniofacial development and associated pathologies.