TASK-5 Polyclonal Antibody

KCNK15 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.

Introducing TASK-5 Polyclonal Antibody, a highly specific and sensitive antibody designed for the detection of TASK-5 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human TASK-5 protein. The resulting polyclonal antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence applications.

TASK-5 is a member of the two-pore domain potassium channel family, which plays a crucial role in regulating the resting membrane potential and excitability of cells. Dysregulation of TASK-5 has been implicated in various pathological conditions, including epilepsy, depression, and chronic pain. Therefore, the availability of a reliable and specific antibody for the detection of TASK-5 protein is essential for understanding its physiological and pathological functions.

The TASK-5 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using the immunizing peptide. The antibody is provided in a liquid form, ready to use for various applications. The antibody has been validated for its specificity and sensitivity in various cell lines and tissues, including brain, heart, and kidney. The antibody has also been shown to detect endogenous TASK-5 protein in human and mouse tissues.

In summary, the TASK-5 Polyclonal Antibody is a highly specific and sensitive tool for the detection of TASK-5 protein in various biological samples. The antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. The availability of this antibody will facilitate the study of TASK-5 function in health and disease and may lead to the development of novel therapeutic strategies for the treatment of TASK-5-related disorders.