TAF II p18 Polyclonal Antibody

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF13 (TATA-box binding protein associated factor 13) encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6.

The TAF II p18 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of TAF II p18 protein expression in various biological samples. This antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the TAF II p18 protein.

The TAF II p18 Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and precise identification of TAF II p18 protein in Western blotting, immunohistochemistry, and immunofluorescence applications. It recognizes endogenous levels of TAF II p18 protein, making it an ideal choice for studying the expression and localization of this protein in different tissues and cell types.

With its high affinity and low background, the TAF II p18 Polyclonal Antibody ensures reliable and reproducible results, facilitating robust and insightful research outcomes. It is manufactured under stringent quality control measures to ensure batch-to-batch consistency and optimal performance.

The TAF II p18 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is available in various sizes to accommodate different experimental needs. Each vial is carefully packaged and stored under recommended conditions to maintain its stability and integrity.

In summary, the TAF II p18 Polyclonal Antibody is a valuable tool for researchers investigating the role and function of TAF II p18 protein. Its exceptional specificity, sensitivity, and reliability make it an indispensable asset in various molecular biology and biomedical research applications.