Spectrin Beta II Polyclonal Antibody

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. SPTBN1 (spectrin beta, non-erythrocytic 1) is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for SPTBN1.

The Spectrin Beta II Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Spectrin Beta II protein in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, ensuring accurate and reproducible results.

The Spectrin Beta II Polyclonal Antibody is produced using state-of-the-art techniques, guaranteeing high purity and batch-to-batch consistency. It is derived from a host animal that has been immunized with a purified recombinant Spectrin Beta II protein, resulting in the generation of a polyclonal antibody with a broad range of epitope recognition.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, immunofluorescence, and flow cytometry. It has been optimized for use in both research and diagnostic settings, enabling the investigation of Spectrin Beta II protein expression and localization in various tissues and cell types.

The Spectrin Beta II Polyclonal Antibody offers exceptional performance, exhibiting minimal background and high signal-to-noise ratio. It provides reliable and accurate results, allowing for the precise quantification and characterization of Spectrin Beta II protein in biological samples.

With its superior quality and performance, the Spectrin Beta II Polyclonal Antibody is an indispensable tool for researchers and clinicians working in the field of cell biology, immunology, and molecular biology. It enables the elucidation of the functional role of Spectrin Beta II protein in various physiological and pathological processes, contributing to a better understanding of cellular mechanisms and disease progression.