SOCS-2 Polyclonal Antibody

SOCS2 encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. Suppressor of cytokine signaling 2 encoded by SOCS2 interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants.

The SOCS-2 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Suppressor of Cytokine Signaling 2 (SOCS-2) protein in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.

The SOCS-2 Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and minimal cross-reactivity, enabling accurate and reliable results.

This antibody is manufactured using state-of-the-art facilities and stringent quality control measures to ensure batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation, ready to use for immediate experimentation.

The SOCS-2 Polyclonal Antibody is an essential tool for researchers studying the role of SOCS-2 in cellular signaling pathways and its implications in various diseases. Its high specificity and sensitivity make it an ideal choice for both basic research and clinical applications.

Order the SOCS-2 Polyclonal Antibody today and unlock new insights into the intricate mechanisms of cellular signaling.