Slit3 Polyclonal Antibody

The protein encoded by SLIT3 (slit guidance ligand 3) is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for SLIT3.

The Slit3 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of Slit3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Slit3 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards Slit3 protein, making it an ideal reagent for various applications such as Western blotting, immunohistochemistry, and ELISA.

The Slit3 Polyclonal Antibody is purified using a combination of protein A and peptide affinity chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody has been extensively validated for its specificity and sensitivity in various biological samples, including human, mouse, and rat tissues. It has also been shown to detect endogenous Slit3 protein expression in various cell lines.

The Slit3 protein is a member of the Slit family of secreted glycoproteins that play a crucial role in axon guidance, cell migration, and tissue morphogenesis. Dysregulation of Slit3 expression has been implicated in various diseases, including cancer, cardiovascular diseases, and neurological disorders. Therefore, the Slit3 Polyclonal Antibody is a valuable tool for researchers studying the role of Slit3 protein in various physiological and pathological processes.

In summary, the Slit3 Polyclonal Antibody is a highly specific and sensitive immunological tool that enables the detection and quantification of Slit3 protein in various biological samples. Its high affinity and specificity make it an ideal reagent for various applications in research and diagnostics.