SLC43A1 Polyclonal Antibody

SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al. 2003 [PubMed 12930836]). supplied by OMIM, Mar 2008]SLC43A1 (Solute Carrier Family 43 Member 1) is a Protein Coding gene. Diseases associated with SLC43A1 include prostate cancer. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include neutral amino acid transmembrane transporter activity and L-amino acid transmembrane transporter activity. An important paralog of this gene is ENSG00000254979. Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.

The SLC43A1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of SLC43A1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human SLC43A1 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The SLC43A1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes a single band of approximately 60 kDa in Western blot analysis of human, mouse, and rat tissue lysates. In addition, it shows strong staining of SLC43A1 protein in formalin-fixed, paraffin-embedded human tissues, including liver, kidney, and lung.

This antibody is an essential tool for researchers studying the function and regulation of SLC43A1 protein in various physiological and pathological conditions. It can be used to investigate the role of SLC43A1 in amino acid transport, metabolism, and signaling pathways. It can also be used to monitor the expression and localization of SLC43A1 in different tissues and cell types.

Overall, the SLC43A1 Polyclonal Antibody is a reliable and high-quality reagent that can provide valuable insights into the biology of SLC43A1 protein. Its specificity, sensitivity, and versatility make it an ideal choice for a wide range of research applications.