SIRP- Alpha1/Beta1 Polyclonal Antibody

The signal regulatory protein alpha encoded by SIRPA is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.

The SIRP-Alpha1/Beta1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of SIRP-Alpha1 and SIRP-Beta1 proteins. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reproducibility.

With its exceptional sensitivity and specificity, the SIRP-Alpha1/Beta1 Polyclonal Antibody enables accurate identification and quantification of SIRP-Alpha1 and SIRP-Beta1 proteins in various biological samples. It is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The SIRP-Alpha1/Beta1 Polyclonal Antibody exhibits excellent performance in both research and clinical settings. Its high affinity and selectivity make it an ideal choice for studying the role of SIRP-Alpha1 and SIRP-Beta1 in various physiological and pathological processes. Furthermore, its versatility allows for the investigation of these proteins in different species, including human, mouse, and rat.

This antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It is provided in a liquid form, allowing for easy handling and minimizing the risk of contamination. The SIRP-Alpha1/Beta1 Polyclonal Antibody is also available in different sizes to accommodate various experimental needs.

In summary, the SIRP-Alpha1/Beta1 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of SIRP-Alpha1 and SIRP-Beta1 proteins. Its exceptional performance, versatility, and convenience make it an indispensable asset for researchers and clinicians alike in their pursuit of understanding the intricate mechanisms underlying various biological processes.