SIRP- Alpha1 Polyclonal Antibody

SIRPA encoded by Tyrosine-protein phosphatase non-receptor type substrate 1 is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.

The SIRP-Alpha1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of SIRP-Alpha1 protein in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity. With its exceptional performance, this antibody enables accurate and precise identification of SIRP-Alpha1, facilitating comprehensive research in the field of immunology and cell biology.

The SIRP-Alpha1 Polyclonal Antibody exhibits excellent specificity, exhibiting minimal cross-reactivity with other proteins, thereby minimizing false-positive results. Its robustness and reproducibility make it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and flow cytometry.

This antibody is manufactured under stringent quality control measures, guaranteeing batch-to-batch consistency and reliability. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. The SIRP-Alpha1 Polyclonal Antibody is compatible with various sample types, including cell lysates, tissue extracts, and serum, ensuring versatility and flexibility in experimental design.

In summary, the SIRP-Alpha1 Polyclonal Antibody is a superior research tool that offers exceptional performance, specificity, and reliability. Its application in various techniques and compatibility with diverse sample types make it an indispensable asset for scientists and researchers in the field of immunology and cell biology.