Sin3B Polyclonal Antibody

SIN3B (SIN3 Transcription Regulator Family Member B) is a Protein Coding gene. Paired amphipathic helix protein Sin3b acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. Among its related pathways are Gene Expression and Metabolism. Gene Ontology (GO) annotations related to this gene include chromatin binding and RNA polymerase II transcription corepressor activity. An important paralog of this gene is SIN3A.

The Sin3B Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Sin3B protein expression in various biological samples. This antibody is produced using advanced recombinant technology, ensuring high affinity and sensitivity.

Sin3B is a crucial component of the Sin3 histone deacetylase complex, which plays a pivotal role in the regulation of gene expression and chromatin remodeling. The Sin3B Polyclonal Antibody recognizes the Sin3B protein with exceptional specificity, enabling accurate and precise identification of Sin3B in a wide range of experimental applications.

This antibody has been extensively validated for use in immunohistochemistry, western blotting, and immunofluorescence assays. It exhibits excellent performance in detecting endogenous Sin3B protein levels, making it an ideal choice for both basic research and clinical investigations.

The Sin3B Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The antibody is also compatible with various detection systems and can be used in combination with other antibodies for multiplex analysis.

With its exceptional specificity, sensitivity, and versatility, the Sin3B Polyclonal Antibody is an indispensable tool for researchers and scientists studying the intricate mechanisms of gene regulation and chromatin remodeling. Trust in its reliability and accuracy to advance your research and uncover new insights in the field of molecular biology.