SH-PTP2 Polyclonal Antibody

Tyrosine-protein phosphatase non-receptor type 11 encoded by PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.

The SH-PTP2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of SH-PTP2 protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The SH-PTP2 Polyclonal Antibody exhibits a high affinity and specificity towards the SH-PTP2 protein, enabling precise and sensitive detection even at low expression levels. Its exceptional sensitivity and low background noise make it an ideal choice for quantitative analysis and precise localization studies.

This antibody has been rigorously tested and validated using a variety of experimental techniques and sample types, ensuring consistent and reliable results. Its superior performance is attributed to the careful selection of high-quality immunogens and the use of advanced purification techniques.

The SH-PTP2 Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and error-prone reconstitution steps. The antibody is also available in different sizes to accommodate various experimental needs.

With its exceptional specificity, sensitivity, and reliability, the SH-PTP2 Polyclonal Antibody is an indispensable tool for researchers studying SH-PTP2 protein function and its involvement in various cellular processes. Its high-quality performance and ease of use make it an excellent choice for both basic research and clinical applications.