SHIP-1 Polyclonal Antibody

INPP5D is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. Alternative splicing of this gene results in multiple transcript variants.

The SHIP-1 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of SHIP-1 protein expression in various biological samples. This antibody has been extensively validated for its exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications.

The SHIP-1 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high affinity and specificity towards the target protein. It has been rigorously tested to exhibit minimal cross-reactivity with other proteins, ensuring accurate and reliable results.

This antibody is designed to recognize the SHIP-1 protein, a key regulator of cellular signaling pathways. By targeting SHIP-1, researchers can gain valuable insights into the modulation of phosphoinositide signaling, cellular proliferation, and immune responses.

The SHIP-1 Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps.

With its exceptional sensitivity and specificity, the SHIP-1 Polyclonal Antibody is an indispensable tool for researchers studying cellular signaling pathways, immunology, and cancer biology. Its reliable performance and ease of use make it an ideal choice for a wide range of applications in both academic and industrial settings.

Choose the SHIP-1 Polyclonal Antibody for accurate and reproducible results in your research endeavors.