Shc Polyclonal Antibody

SHC1 (SHC adaptor protein 1) encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for SHC1.

The SHC Polyclonal Antibody is a highly reliable and efficient tool for various research applications. This antibody is specifically designed to target the SHC protein, a key regulator of cellular signaling pathways. With its exceptional specificity and sensitivity, this polyclonal antibody enables accurate detection and analysis of SHC protein expression levels in a wide range of biological samples.

The SHC Polyclonal Antibody is produced using state-of-the-art techniques, ensuring consistent and high-quality results. It has been extensively validated for use in various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody exhibits minimal cross-reactivity with other proteins, ensuring reliable and specific detection of the SHC protein.

In addition to its exceptional performance, the SHC Polyclonal Antibody offers ease of use and convenience. It is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. The antibody is also compatible with a variety of sample types, including cell lysates, tissue extracts, and purified proteins.

Researchers can rely on the SHC Polyclonal Antibody to provide accurate and reproducible results, facilitating their investigations into the role of the SHC protein in various cellular processes. Whether studying signal transduction pathways, cell proliferation, or apoptosis, this antibody is an invaluable tool for elucidating the molecular mechanisms underlying these biological phenomena.

Choose the SHC Polyclonal Antibody for its exceptional performance, reliability, and ease of use. Accelerate your research and gain valuable insights into the intricate world of cellular signaling with this highly effective antibody.