Shank 2 Polyclonal Antibody

SHANK2 encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain. Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants.

The Shank 2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Shank 2 protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Shank 2 Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling the detection of even low levels of Shank 2 protein with minimal background interference. This antibody has been rigorously tested and validated using a variety of experimental conditions and sample types, ensuring consistent and reproducible results.

With its high affinity and selectivity, the Shank 2 Polyclonal Antibody offers researchers a valuable tool for investigating the role of Shank 2 in various biological processes and diseases. Its versatility allows for the examination of Shank 2 expression and localization in different tissues and cell types, providing valuable insights into its function and regulation.

The Shank 2 Polyclonal Antibody is manufactured using state-of-the-art techniques and quality control measures to ensure batch-to-batch consistency and reliability. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation.

In summary, the Shank 2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Shank 2 protein expression. Its exceptional sensitivity, specificity, and versatility make it an invaluable asset for researchers studying the role of Shank 2 in various biological processes and diseases.