Septin 5 Polyclonal Antibody

SEPT5 (septin 5) is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. SEPT5 is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and SEPT5 has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

The Septin 5 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Septin 5 protein in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in research applications.

Septin 5 is a crucial component of the septin family of GTP-binding proteins, which play essential roles in diverse cellular processes, including cell division, cytoskeletal organization, and membrane dynamics. The Septin 5 Polyclonal Antibody specifically recognizes and binds to Septin 5, enabling precise identification and quantification of this protein in complex biological systems.

This antibody has been rigorously tested for its specificity, sensitivity, and reproducibility, ensuring reliable and consistent results. It exhibits minimal cross-reactivity with other septin family members, ensuring accurate detection of Septin 5 without interference from closely related proteins.

The Septin 5 Polyclonal Antibody is suitable for various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It has been optimized for use in both human and animal samples, making it a versatile tool for a wide range of research applications.

With its high affinity and specificity, the Septin 5 Polyclonal Antibody offers researchers a valuable tool for investigating the functional roles and regulatory mechanisms of Septin 5 in cellular processes. Its exceptional performance and reliability make it an indispensable asset for any laboratory conducting research in the field of cell biology, molecular biology, or related disciplines.

Order the Septin 5 Polyclonal Antibody today and unlock new insights into the intricate workings of cellular processes mediated by Septin 5. Trust in its exceptional quality and performance to advance your research and contribute to scientific discoveries.