Septin 3 Polyclonal Antibody

SEPT3 belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

The Septin 3 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Septin 3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Septin 3 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The Septin 3 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize human Septin 3 protein with minimal cross-reactivity to other Septin family members. The antibody has also been shown to detect endogenous Septin 3 protein in various human tissues, including brain, heart, kidney, liver, and lung.

This antibody is an essential tool for researchers studying the role of Septin 3 protein in various biological processes, including cell division, cytoskeletal organization, and neuronal development. It can also be used for diagnostic purposes in clinical settings, such as the detection of Septin 3 protein in cancer tissues.

In summary, the Septin 3 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of Septin 3 protein in various biological samples. Its high quality and reliability make it an essential tool for researchers and clinicians alike.